For Parents

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Avalglucosidase Alfa Injection (AVALGLUCOSIDASE ALFA - INJECTION)

For genetic disorder.

Brand Name(s): Nexviazyme

Generic Name: Avalglucosidase Alfa-ngpt

Instructions

This medicine is given as an IV injection into a vein.

This medicine should be given by a trained health care provider.

You must be monitored by a health care professional during and after each dose is given.

It is important that you keep taking each dose of this medicine on time even if you are feeling well.

If you miss a dose, contact your doctor for instructions.

Drug interactions can change how medicines work or increase risk for side effects. Tell your health care providers about all medicines taken. Include prescription and over-the-counter medicines, vitamins, and herbal medicines. Speak with your doctor or pharmacist before starting or stopping any medicine.

Keep all appointments for medical exams and tests while on this medicine.

Cautions

During pregnancy, this medicine should be used only when clearly needed. Talk to your doctor about the risks and benefits.

Tell your doctor and pharmacist if you ever had an allergic reaction to a medicine.

Some patients taking this medicine have experienced serious side effects. Please speak with your doctor to understand the risks and benefits associated with this medicine.

Tell your doctor or nurse right away if chest pain, severe dizziness, skin rash, itching, difficulty breathing, feeling of heat or flushing, or swelling of the face or throat develop while the medicine is being given. The medicine may need to be stopped or given at a slower rate.

There is a pregnancy registry for women who use this medicine while pregnant. Ask your doctor or pharmacist how to enroll if you are pregnant or become pregnant while taking this medicine.

It is unknown if this medicine passes into breast milk. Ask your doctor before breastfeeding.

Side Effects

The following is a list of some common side effects from this medicine. Please speak with your doctor about what you should do if you experience these or other side effects.

  • diarrhea
  • lack of energy and tiredness
  • headaches
  • joint or muscle pain
  • nausea and vomiting

Call your doctor or get medical help right away if you notice any of these more serious side effects:

  • severe allergic reaction
  • chest pain
  • dizziness
  • feeling of heat or flushing
  • red, burning, or itchy skin
  • shortness of breath

A few people may have an allergic reaction to this medicine. Symptoms can include difficulty breathing, skin rash, itching, swelling, or severe dizziness. If you notice any of these symptoms, seek medical help quickly.

Please speak with your doctor, nurse, or pharmacist if you have any questions about this medicine.